Homo sapiens Gene: PKN2
Summary
InnateDB Gene IDBG-100129.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PKN2
Gene Name protein kinase N2
Synonyms Pak-2; PAK2; PRK2; PRKCL2; PRO2042; STK7;
Species Homo sapiens
Ensembl Gene ENSG00000065243
Encoded Proteins
protein kinase N2
protein kinase N2
protein kinase N2
protein kinase N2
protein kinase N2
protein kinase N2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:88684222-88836255
Strand Forward strand
Band p22.2
Transcripts
ENST00000370521 ENSP00000359552
ENST00000316005 ENSP00000317851
ENST00000370513 ENSP00000359544
ENST00000370505 ENSP00000359536
ENST00000436111 ENSP00000401125
ENST00000449189 ENSP00000389076
ENST00000495119
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 49 experimentally validated interaction(s) in this database.
Experimentally validated
Total 49 [view]
Protein-Protein 44 [view]
Protein-DNA 4 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004697 protein kinase C activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0042826 histone deacetylase binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006468 protein phosphorylation
GO:0006915 apoptotic process
GO:0007049 cell cycle
GO:0007155 cell adhesion
GO:0007165 signal transduction
GO:0010631 epithelial cell migration
GO:0016310 phosphorylation
GO:0032467 positive regulation of cytokinesis
GO:0043297 apical junction assembly
GO:0045931 positive regulation of mitotic cell cycle
GO:0051301 cell division
GO:2000145 regulation of cell motility
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0016020 membrane
GO:0030027 lamellipodium
GO:0030496 midbody
GO:0032154 cleavage furrow
GO:0043296 apical junction complex
GO:0045111 intermediate filament cytoskeleton
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
EGFR1 pathway
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
RhoA signaling pathway
Cross-References
SwissProt
TrEMBL B1AL79
UniProt Splice Variant
Entrez Gene 5586
UniGene Hs.440833 Hs.635447 Hs.703016
RefSeq NM_006256
HUGO HGNC:9406
OMIM 602549
CCDS CCDS714
HPRD 03972
IMGT
EMBL AC119426 AL136381 CH471097
GenPept EAW73162
RNA Seq Atlas 5586