Bos taurus Gene: ALDH3A1 | |||||||||||||||||
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Summary | |||||||||||||||||
InnateDB Gene | IDBG-637681.3 | ||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
Gene Symbol | ALDH3A1 | ||||||||||||||||
Gene Name | aldehyde dehydrogenase, dimeric NADP-preferring | ||||||||||||||||
Synonyms | ALDH3 | ||||||||||||||||
Species | Bos taurus | ||||||||||||||||
Ensembl Gene | ENSBTAG00000021113 | ||||||||||||||||
Encoded Proteins |
aldehyde dehydrogenase, dimeric NADP-preferring
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Protein Structure | |||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
Entrez Gene | |||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000108602:
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008] |
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Gene Information | |||||||||||||||||
Type | Protein coding | ||||||||||||||||
Genomic Location | Chromosome 19:34483124-34489156 | ||||||||||||||||
Strand | Forward strand | ||||||||||||||||
Band | |||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||||
NETPATH | |||||||||||||||||
REACTOME | |||||||||||||||||
KEGG |
Glycolysis / Gluconeogenesis pathway
Histidine metabolism pathway
Phenylalanine metabolism pathway
Tyrosine metabolism pathway
beta-Alanine metabolism pathway
Metabolism of xenobiotics by cytochrome P450 pathway
Drug metabolism pathway
beta-Alanine metabolism pathway
Tyrosine metabolism pathway
Histidine metabolism pathway
Glycolysis / Gluconeogenesis pathway
Phenylalanine metabolism pathway
Metabolism of xenobiotics by cytochrome P450 pathway
Drug metabolism pathway
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INOH |
Phenylalanine degradation pathway
Tyrosine metabolism pathway
Histidine degradation pathway
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PID NCI | |||||||||||||||||
Cross-References | |||||||||||||||||
SwissProt | |||||||||||||||||
TrEMBL | F1N015 | ||||||||||||||||
UniProt Splice Variant | |||||||||||||||||
Entrez Gene | 281617 | ||||||||||||||||
UniGene | Bt.13116 | ||||||||||||||||
RefSeq | NM_001166513 | ||||||||||||||||
HUGO | |||||||||||||||||
OMIM | |||||||||||||||||
CCDS | |||||||||||||||||
HPRD | |||||||||||||||||
IMGT | |||||||||||||||||
EMBL | DAAA02048976 | ||||||||||||||||
GenPept | |||||||||||||||||
RNA Seq Atlas | 281617 | ||||||||||||||||