Version 5.4
Bos taurus Gene: UBE2T
Summary
InnateDB Gene IDBG-637970.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UBE2T
Gene Name Ubiquitin-conjugating enzyme E2 T
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004790
Encoded Proteins
IDBP-690005
ubiquitin-conjugating enzyme E2 T
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000077152:
The covalent conjugation of ubiquitin to proteins regulates diverse cellular pathways and proteins. Ubiquitin is transferred to a target protein through a concerted action of a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), such as UBE2T, and a ubiquitin ligase (E3) (Machida et al., 2006 [PubMed 16916645]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:71019535-71024141
Strand Reverse strand
Band
Transcripts
ENSBTAT00000006290 ENSBTAP00000006290
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003682 chromatin binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0016881 acid-amino acid ligase activity
GO:0031625 ubiquitin protein ligase binding
Biological Process
GO:0006281 DNA repair
GO:0006513 protein monoubiquitination
GO:0006974 cellular response to DNA damage stimulus
GO:0016567 protein ubiquitination
GO:0035519 protein K29-linked ubiquitination
GO:0044314 protein K27-linked ubiquitination
GO:0051865 protein autoubiquitination
GO:0070534 protein K63-linked ubiquitination
GO:0070936 protein K48-linked ubiquitination
GO:0070979 protein K11-linked ubiquitination
GO:0085020 protein K6-linked ubiquitination
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000077152
View Gene Order
ENSMUSG00000026429
View Gene Order
Pathways
NETPATH
REACTOME
REACT_204262
DNA Repair pathway
REACT_205389
Fanconi Anemia pathway pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_18410
Fanconi Anemia pathway pathway
REACT_216
DNA Repair pathway
REACT_233397
DNA Repair pathway
REACT_232842
Fanconi Anemia pathway pathway
KEGG
INOH
PID NCI
fanconi_pathway
Fanconi anemia pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.2915
RefSeq NM_001038034 XM_005217331 XM_005217332
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca