InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.28410

Summary

InnateDB Gene

IDBG-638504.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.28410

Gene Name

hormone-sensitive lipase

Synonyms

hsl

Species

Bos taurus

Ensembl Gene

ENSBTAG00000038321

Encoded Proteins

IDBP-690575

hormone-sensitive lipase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000079435:
The protein encoded by this gene has a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesteryl esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 18:51216019-51227395

Strand

Forward strand

Band

Transcripts

ENSBTAT00000043890

ENSBTAP00000041426

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004806	triglyceride lipase activity
GO:0005515	protein binding
GO:0016298	lipase activity
GO:0016787	hydrolase activity
GO:0019901	protein kinase binding

Biological Process

GO:0008152	metabolic process
GO:0008203	cholesterol metabolic process
GO:0016042	lipid catabolic process
GO:0042758	long-chain fatty acid catabolic process
GO:0046340	diacylglycerol catabolic process