Version 5.4
Bos taurus Gene: PALB2
Summary
InnateDB Gene IDBG-638524.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PALB2
Gene Name partner and localizer of BRCA2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000006405
Encoded Proteins
IDBP-690606
partner and localizer of BRCA2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000083093:
This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 25:21516078-21540686
Strand Reverse strand
Band
Transcripts
ENSBTAT00000008398 ENSBTAP00000008398
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0001756 somitogenesis
GO:0001833 inner cell mass cell proliferation
GO:0006355 regulation of transcription, DNA-templated
GO:0007498 mesoderm development
GO:0009887 organ morphogenesis
GO:0036342 post-anal tail morphogenesis
GO:0043066 negative regulation of apoptotic process
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000083093
View Gene Order
ENSMUSG00000044702
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_18410
Fanconi Anemia pathway pathway
REACT_216
DNA Repair pathway
REACT_233397
DNA Repair pathway
REACT_232842
Fanconi Anemia pathway pathway
KEGG
INOH
PID NCI
fanconi_pathway
Fanconi anemia pathway
Cross-References
SwissProt
TrEMBL E1BL90
UniProt Splice Variant
Entrez Gene 507620
UniGene Bt.51708
RefSeq NM_001205615
HUGO HGNC:26144
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02057764
GenPept
RNA Seq Atlas 507620

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca