Version 5.4
Mus musculus Gene: Palb2
Summary
InnateDB Gene IDBG-208870.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Palb2
Gene Name partner and localizer of BRCA2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000044702
Encoded Proteins
IDBP-208872
partner and localizer of BRCA2
IDBP-208874
partner and localizer of BRCA2
IDBP-268709
partner and localizer of BRCA2
IDBP-268711
partner and localizer of BRCA2
IDBP-537200
partner and localizer of BRCA2
IDBP-541906
partner and localizer of BRCA2
IDBP-539970
partner and localizer of BRCA2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000083093:
This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:122107262-122132946
Strand Reverse strand
Band F2
Transcripts
ENSMUST00000063587 ENSMUSP00000063514
ENSMUST00000098068 ENSMUSP00000095675
ENSMUST00000106469 ENSMUSP00000102077
ENSMUST00000106468 ENSMUSP00000102076
ENSMUST00000154508
ENSMUST00000131657 ENSMUSP00000118059
ENSMUST00000142952 ENSMUSP00000123041
ENSMUST00000130149 ENSMUSP00000121994
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0001756 somitogenesis
GO:0001833 inner cell mass cell proliferation
GO:0007498 mesoderm development
GO:0009887 organ morphogenesis
GO:0036342 post-anal tail morphogenesis
GO:0043066 negative regulation of apoptotic process
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000083093
View Gene Order
ENSBTAG00000006405
Not yet available
Pathways
NETPATH
REACTOME
REACT_233397
DNA Repair pathway
REACT_232842
Fanconi Anemia pathway pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_18410
Fanconi Anemia pathway pathway
REACT_216
DNA Repair pathway
KEGG
INOH
PID NCI
fanconi_pathway
Fanconi anemia pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.38348
RefSeq NM_001081238 NM_001289842 NM_001289843 NM_001289844 NM_001289845 XM_006507701 XM_006507703 XM_006507704
OMIM
CCDS CCDS40117 CCDS72035
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca