Bos taurus Gene: NCK1 | |||||||||||||||||||||
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Summary | |||||||||||||||||||||
InnateDB Gene | IDBG-638662.3 | ||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||
Gene Symbol | NCK1 | ||||||||||||||||||||
Gene Name | cytoplasmic protein NCK1 | ||||||||||||||||||||
Synonyms | |||||||||||||||||||||
Species | Bos taurus | ||||||||||||||||||||
Ensembl Gene | ENSBTAG00000018427 | ||||||||||||||||||||
Encoded Proteins |
cytoplasmic protein NCK1
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Protein Structure | |||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000158092:
The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Jun 2010] |
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Gene Information | |||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||
Genomic Location | Chromosome 1:133319427-133395740 | ||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||
Band | |||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 206 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||
NETPATH |
EGFR1 pathway
TCR pathway
BCR pathway
Prolactin pathway
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REACTOME |
Regulation of actin dynamics for phagocytic cup formation pathway
Generation of second messenger molecules pathway
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers pathway
Downstream signal transduction pathway
Signaling by PDGF pathway
Nephrin interactions pathway
DCC mediated attractive signaling pathway
Netrin-1 signaling pathway
Activation of Rac pathway
Signaling by Robo receptor pathway
Developmental Biology pathway
Cell-Cell communication pathway
TCR signaling pathway
Signaling by VEGF pathway
Innate Immune System pathway
Axon guidance pathway
Signal Transduction pathway
Adaptive Immune System pathway
Immune System pathway
VEGFA-VEGFR2 Pathway pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
Signaling by the B Cell Receptor (BCR) pathway
Innate Immune System pathway
Regulation of actin dynamics for phagocytic cup formation pathway
Signaling by the B Cell Receptor (BCR) pathway
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers pathway
Nephrin interactions pathway
Netrin-1 signaling pathway
Signaling by VEGF pathway
Immune System pathway
Downstream signal transduction pathway
Signaling by Robo receptor pathway
DCC mediated attractive signaling pathway
VEGFA-VEGFR2 Pathway pathway
Axon guidance pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
Adaptive Immune System pathway
Signaling by PDGF pathway
Developmental Biology pathway
Signal Transduction pathway
Generation of second messenger molecules pathway
Cell-Cell communication pathway
Activation of Rac pathway
TCR signaling pathway
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KEGG |
Pathogenic Escherichia coli infection pathway
ErbB signaling pathway pathway
Axon guidance pathway
T cell receptor signaling pathway pathway
Axon guidance pathway
ErbB signaling pathway pathway
T cell receptor signaling pathway pathway
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INOH |
PDGF signaling pathway pathway
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PID NCI |
Netrin-mediated signaling events
TCR signaling in naïve CD4+ T cells
EPHB forward signaling
Angiopoietin receptor Tie2-mediated signaling
Signaling events regulated by Ret tyrosine kinase
VEGFR1 specific signals
Stabilization and expansion of the E-cadherin adherens junction
Arf6 signaling events
Insulin Pathway
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Cross-References | |||||||||||||||||||||
SwissProt | |||||||||||||||||||||
TrEMBL | |||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||
UniGene | Bt.46490 | ||||||||||||||||||||
RefSeq | NM_001076072 XM_005201879 XM_005201880 XM_005201881 | ||||||||||||||||||||
HUGO | |||||||||||||||||||||
OMIM | |||||||||||||||||||||
CCDS | |||||||||||||||||||||
HPRD | |||||||||||||||||||||
IMGT | |||||||||||||||||||||
EMBL | |||||||||||||||||||||
GenPept | |||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||