|Bos taurus Gene: SPOP|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||Speckle-type POZ protein|
Speckle-type POZ protein
|Useful resources||Stemformatics EHFPI ImmGen|
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000121067:
This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
|Genomic Location||Chromosome 19:37570928-37653473|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.
|Pathway Predictions based on Human Orthology Data|
Hedgehog signaling events mediated by Gli proteins
|UniProt Splice Variant|
|RefSeq||NM_001075936 XM_005220571 XM_005220572|
|RNA Seq Atlas||530618|