Version 5.4
| Bos taurus Gene: ARHGEF1 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-638817.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | ARHGEF1 | ||||||||
| Gene Name | Uncharacterized protein | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000018912 | ||||||||
| Encoded Proteins |
Rho guanine nucleotide exchange factor (GEF) 1
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000076928:
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 18:51658123-51678112 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH |
TNFalpha pathway
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| REACTOME |
Axonal growth inhibition (RHOA activation) pathway
G alpha (12/13) signalling events pathway
Signalling by NGF pathway
p75NTR regulates axonogenesis pathway
Signaling by GPCR pathway
p75 NTR receptor-mediated signalling pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR downstream signaling pathway
p75NTR regulates axonogenesis pathway
Signaling by GPCR pathway
Axonal growth inhibition (RHOA activation) pathway
G alpha (12/13) signalling events pathway
Signalling by NGF pathway
Signal Transduction pathway
p75 NTR receptor-mediated signalling pathway
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| KEGG |
Regulation of actin cytoskeleton pathway
Vascular smooth muscle contraction pathway
Regulation of actin cytoskeleton pathway
Vascular smooth muscle contraction pathway
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| INOH | |||||||||
| PID NCI |
Thromboxane A2 receptor signaling
LPA receptor mediated events
PAR1-mediated thrombin signaling events
Regulation of RhoA activity
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | E1BG38 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 513377 | ||||||||
| UniGene | Bt.21775 | ||||||||
| RefSeq | XM_002695075 XM_591046 | ||||||||
| HUGO | HGNC:681 | ||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | DAAA02047237 DAAA02047238 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 513377 | ||||||||