Bos taurus Gene: ARHGEF1 | |||||||||
---|---|---|---|---|---|---|---|---|---|
Summary | |||||||||
InnateDB Gene | IDBG-638817.3 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | ARHGEF1 | ||||||||
Gene Name | Uncharacterized protein | ||||||||
Synonyms | |||||||||
Species | Bos taurus | ||||||||
Ensembl Gene | ENSBTAG00000018912 | ||||||||
Encoded Proteins |
Rho guanine nucleotide exchange factor (GEF) 1
|
||||||||
Protein Structure | |||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||
Entrez Gene | |||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000076928:
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008] |
||||||||
Gene Information | |||||||||
Type | Protein coding | ||||||||
Genomic Location | Chromosome 18:51658123-51678112 | ||||||||
Strand | Reverse strand | ||||||||
Band | |||||||||
Transcripts |
|
||||||||
Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.
|
||||||||
Gene Ontology | |||||||||
Molecular Function |
|
||||||||
Biological Process |
|
||||||||
Cellular Component |
|
||||||||
Orthologs | |||||||||
Species
Homo sapiens
Mus musculus
|
Gene ID
Gene Order
|
||||||||
Pathway Predictions based on Human Orthology Data | |||||||||
NETPATH |
TNFalpha pathway
|
||||||||
REACTOME |
Axonal growth inhibition (RHOA activation) pathway
G alpha (12/13) signalling events pathway
Signalling by NGF pathway
p75NTR regulates axonogenesis pathway
Signaling by GPCR pathway
p75 NTR receptor-mediated signalling pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR downstream signaling pathway
p75NTR regulates axonogenesis pathway
Signaling by GPCR pathway
Axonal growth inhibition (RHOA activation) pathway
G alpha (12/13) signalling events pathway
Signalling by NGF pathway
Signal Transduction pathway
p75 NTR receptor-mediated signalling pathway
|
||||||||
KEGG |
Regulation of actin cytoskeleton pathway
Vascular smooth muscle contraction pathway
Regulation of actin cytoskeleton pathway
Vascular smooth muscle contraction pathway
|
||||||||
INOH | |||||||||
PID NCI |
Thromboxane A2 receptor signaling
LPA receptor mediated events
PAR1-mediated thrombin signaling events
Regulation of RhoA activity
|
||||||||
Cross-References | |||||||||
SwissProt | |||||||||
TrEMBL | E1BG38 | ||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | 513377 | ||||||||
UniGene | Bt.21775 | ||||||||
RefSeq | XM_002695075 XM_591046 | ||||||||
HUGO | HGNC:681 | ||||||||
OMIM | |||||||||
CCDS | |||||||||
HPRD | |||||||||
IMGT | |||||||||
EMBL | DAAA02047237 DAAA02047238 | ||||||||
GenPept | |||||||||
RNA Seq Atlas | 513377 | ||||||||