InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: LDHB

Summary

InnateDB Gene

IDBG-638957.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LDHB

Gene Name

L-lactate dehydrogenase B chain

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000019603

Encoded Proteins

IDBP-691068

L-lactate dehydrogenase B chain

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111716:
This gene encodes an enzyme which catalyzes the reversible conversion of lactate and pyruvate, and NAD and NADH, in the glycolytic pathway. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on the X chromosome and on chromosome. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Mar 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:88962679-88981219

Strand

Forward strand

Band

Transcripts

ENSBTAT00000026118

ENSBTAP00000026118

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.

Predicted by orthology
Total	24 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004459	L-lactate dehydrogenase activity
GO:0005515	protein binding
GO:0016491	oxidoreductase activity
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006096	glycolytic process
GO:0044262	cellular carbohydrate metabolic process
GO:0055114	oxidation-reduction process