Bos taurus Gene: LOC790544
InnateDB Gene IDBG-639264.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LOC790544
Gene Name non-specific lipid-transfer protein
Synonyms SCPX
Species Bos taurus
Ensembl Gene ENSBTAG00000003746
Encoded Proteins
non-specific lipid-transfer protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116171:
This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.[provided by RefSeq, Aug 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:93846489-93968364
Strand Reverse strand
ENSBTAT00000004879 ENSBTAP00000004879
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
Predicted by orthology
Total 26 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000062 fatty-acyl-CoA binding
GO:0003824 catalytic activity
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0008526 phosphatidylinositol transporter activity
GO:0015485 cholesterol binding
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
GO:0036042 long-chain fatty acyl-CoA binding
GO:0070538 oleic acid binding
Biological Process
GO:0006694 steroid biosynthetic process
GO:0006701 progesterone biosynthetic process
GO:0007031 peroxisome organization
GO:0008152 metabolic process
GO:0015914 phospholipid transport
GO:0032385 positive regulation of intracellular cholesterol transport
GO:0032959 inositol trisphosphate biosynthetic process
GO:0045940 positive regulation of steroid metabolic process
GO:0072659 protein localization to plasma membrane
GO:1901373 lipid hydroperoxide transport
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005777 peroxisome
GO:0016020 membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0043234 protein complex
GO:0070062 extracellular vesicular exosome
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
alpha-linolenic acid (ALA) metabolism pathway
Metabolism of lipids and lipoproteins pathway
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism pathway
Metabolism pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Synthesis of bile acids and bile salts pathway
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol pathway
alpha-linolenic acid (ALA) metabolism pathway
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism pathway
Beta-oxidation of pristanoyl-CoA pathway
Peroxisomal lipid metabolism pathway
Bile acid and bile salt metabolism pathway
PPAR signaling pathway pathway
Primary bile acid biosynthesis pathway
Peroxisome pathway
Primary bile acid biosynthesis pathway
PPAR signaling pathway pathway
Peroxisome pathway
UniProt Splice Variant
Entrez Gene
UniGene Bt.109019 Bt.11188
RefSeq NM_001033990
RNA Seq Atlas