Bos taurus Gene: GRB7 | |||||||||||||||||
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Summary | |||||||||||||||||
InnateDB Gene | IDBG-639472.3 | ||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
Gene Symbol | GRB7 | ||||||||||||||||
Gene Name | Growth factor receptor-bound protein 7 | ||||||||||||||||
Synonyms | |||||||||||||||||
Species | Bos taurus | ||||||||||||||||
Ensembl Gene | ENSBTAG00000017366 | ||||||||||||||||
Encoded Proteins |
Growth factor receptor-bound protein 7
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Protein Structure | |||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
Entrez Gene | |||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000141738:
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011] |
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Gene Information | |||||||||||||||||
Type | Protein coding | ||||||||||||||||
Genomic Location | Chromosome 19:40753903-40762633 | ||||||||||||||||
Strand | Forward strand | ||||||||||||||||
Band | |||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 39 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathways | |||||||||||||||||
NETPATH | |||||||||||||||||
REACTOME |
Cell surface interactions at the vascular wall pathway
GRB7 events in ERBB2 signaling pathway
Signaling by PDGF pathway
Tie2 Signaling pathway
Hemostasis pathway
Signaling by ERBB2 pathway
Signal Transduction pathway
Downstream signal transduction pathway
Signaling by SCF-KIT pathway
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KEGG | |||||||||||||||||
INOH | |||||||||||||||||
PID NCI | |||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||
NETPATH |
EGFR1 pathway
KitReceptor pathway
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REACTOME |
Tie2 Signaling pathway
Cell surface interactions at the vascular wall pathway
GRB7 events in ERBB2 signaling pathway
Signaling by ERBB2 pathway
Signaling by SCF-KIT pathway
Downstream signal transduction pathway
Signaling by PDGF pathway
Signal Transduction pathway
Hemostasis pathway
Signaling by ERBB2 pathway
Hemostasis pathway
Signaling by SCF-KIT pathway
Cell surface interactions at the vascular wall pathway
Downstream signal transduction pathway
Signaling by PDGF pathway
Signal Transduction pathway
Tie2 Signaling pathway
GRB7 events in ERBB2 signaling pathway
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KEGG | |||||||||||||||||
INOH | |||||||||||||||||
PID NCI |
Signaling events mediated by focal adhesion kinase
EPHB forward signaling
Angiopoietin receptor Tie2-mediated signaling
Signaling events regulated by Ret tyrosine kinase
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Cross-References | |||||||||||||||||
SwissProt | |||||||||||||||||
TrEMBL | |||||||||||||||||
UniProt Splice Variant | |||||||||||||||||
Entrez Gene | |||||||||||||||||
UniGene | Bt.2949 | ||||||||||||||||
RefSeq | NM_001046014 XM_005220694 XM_005220695 XM_005220696 XM_005220697 XM_005220698 XM_005220699 | ||||||||||||||||
HUGO | |||||||||||||||||
OMIM | |||||||||||||||||
CCDS | |||||||||||||||||
HPRD | |||||||||||||||||
IMGT | |||||||||||||||||
EMBL | |||||||||||||||||
GenPept | |||||||||||||||||
RNA Seq Atlas | |||||||||||||||||