Bos taurus Gene: NECAP1
Summary
InnateDB Gene IDBG-639814.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NECAP1
Gene Name Adaptin ear-binding coat-associated protein 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000020237
Encoded Proteins
Adaptin ear-binding coat-associated protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000089818:
This gene encodes a protein containing two characteristic WXXF motifs. The encoded protein localizes to clathrin-coated vesicles, where it binds components of the adapter protein complexes and aids in endocytosis. Loss of function of this gene results in early infantile epileptic encephalopathy-21. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:102050908-102062664
Strand Forward strand
Band
Transcripts
ENSBTAT00000026951 ENSBTAP00000026951
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0006897 endocytosis
GO:0015031 protein transport
Cellular Component
GO:0005886 plasma membrane
GO:0005905 coated pit
GO:0016020 membrane
GO:0030125 clathrin vesicle coat
GO:0030665 clathrin-coated vesicle membrane
GO:0031410 cytoplasmic vesicle
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Golgi Associated Vesicle Biogenesis pathway
Clathrin derived vesicle budding pathway
trans-Golgi Network Vesicle Budding pathway
Membrane Trafficking pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
trans-Golgi Network Vesicle Budding pathway
Clathrin derived vesicle budding pathway
Golgi Associated Vesicle Biogenesis pathway
Membrane Trafficking pathway
Membrane Trafficking pathway
Golgi Associated Vesicle Biogenesis pathway
trans-Golgi Network Vesicle Budding pathway
Clathrin derived vesicle budding pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q3T093
TrEMBL
UniProt Splice Variant
Entrez Gene 504449
UniGene Bt.52837
RefSeq NM_001034211
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102498 BC142418
GenPept AAI02499 AAI42419
RNA Seq Atlas 504449
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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