Version 5.4
Bos taurus Gene: KRT17
Summary
InnateDB Gene IDBG-639920.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KRT17
Gene Name Keratin, type I cytoskeletal 17
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000006806
Encoded Proteins
IDBP-692119
keratin, type I cytoskeletal 17
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000128422:
This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. [provided by RefSeq, Aug 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:42472440-42483976
Strand Reverse strand
Band
Transcripts
ENSBTAT00000008948 ENSBTAP00000008948
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.
Predicted by orthology
Total 28 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005515 protein binding
GO:0032395 MHC class II receptor activity
GO:0042289 MHC class II protein binding
Biological Process
GO:0002009 morphogenesis of an epithelium
GO:0007165 signal transduction
GO:0030307 positive regulation of cell growth
GO:0031424 keratinization
GO:0045109 intermediate filament organization
GO:0045727 positive regulation of translation
GO:0051798 positive regulation of hair follicle development
Cellular Component
GO:0005737 cytoplasm
GO:0005882 intermediate filament
GO:0070062 extracellular vesicular exosome
GO:0071944 cell periphery
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000128422
View Gene Order
ENSMUSG00000035557
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
INOH
PID NCI
reg_gr_pathway
Glucocorticoid receptor regulatory network
Cross-References
SwissProt A1L595
TrEMBL
UniProt Splice Variant
Entrez Gene 281889
UniGene Bt.91540
RefSeq NM_001105322 XM_005220671
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC142137 BT029882
GenPept AAI42138 ABM06133
RNA Seq Atlas 281889

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca