Version 5.4
Mus musculus Gene: Krt17
Summary
InnateDB Gene IDBG-211307.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Krt17
Gene Name keratin 17
Synonyms K17; Krt1-17
Species Mus musculus
Ensembl Gene ENSMUSG00000035557
Encoded Proteins
IDBP-211309
keratin 17
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000128422:
This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. [provided by RefSeq, Aug 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:100256217-100261029
Strand Reverse strand
Band D
Transcripts
ENSMUST00000080893 ENSMUSP00000079699
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005515 protein binding
GO:0032395 MHC class II receptor activity
GO:0042289 MHC class II protein binding
Biological Process
GO:0002009 morphogenesis of an epithelium
GO:0007165 signal transduction
GO:0030307 positive regulation of cell growth
GO:0031424 keratinization
GO:0045109 intermediate filament organization
GO:0045727 positive regulation of translation
GO:0051798 positive regulation of hair follicle development
Cellular Component
GO:0005737 cytoplasm
GO:0005882 intermediate filament
GO:0070062 extracellular vesicular exosome
GO:0071944 cell periphery
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000128422
View Gene Order
ENSBTAG00000006806
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
INOH
PID NCI
reg_gr_pathway
Glucocorticoid receptor regulatory network
Cross-References
SwissProt Q9QWL7
TrEMBL
UniProt Splice Variant
Entrez Gene 16667
UniGene Mm.14046
RefSeq NM_010663
OMIM
CCDS CCDS25415
HPRD
IMGT
MGI ID MGI:96691
MGI Symbol Krt17
EMBL AB013608 AL590873 BC132454 BC132456 M13805
GenPept AAA39394 AAI32455 AAI32457 BAA34229 CAM17780
RNA Seq Atlas 16667

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca