Version 5.4
Bos taurus Gene: NAPA
Summary
InnateDB Gene IDBG-640027.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NAPA
Gene Name alpha-soluble NSF attachment protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013084
Encoded Proteins
IDBP-692237
alpha-soluble NSF attachment protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105402:
This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. The encoded protein plays a role in the completion of membrane fusion by mediating the interaction of N-ethylmaleimide-sensitive factor (NSF) with the vesicle-associated and membrane-associated SNAP receptor (SNARE) complex, and stimulating the ATPase activity of NSF. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:54902551-54928520
Strand Reverse strand
Band
Transcripts
ENSBTAT00000017397 ENSBTAP00000017397
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.
Predicted by orthology
Total 24 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019905 syntaxin binding
Biological Process
GO:0006886 intracellular protein transport
GO:0007420 brain development
GO:0010807 regulation of synaptic vesicle priming
GO:0030182 neuron differentiation
GO:0035249 synaptic transmission, glutamatergic
GO:0035494 SNARE complex disassembly
GO:0045176 apical protein localization
Cellular Component
GO:0016020 membrane
GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000105402
View Gene Order
ENSMUSG00000006024
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19400
Golgi Associated Vesicle Biogenesis pathway
REACT_19187
Clathrin derived vesicle budding pathway
REACT_11235
trans-Golgi Network Vesicle Budding pathway
REACT_11123
Membrane Trafficking pathway
REACT_209837
Membrane Trafficking pathway
REACT_232671
Golgi Associated Vesicle Biogenesis pathway
REACT_243409
trans-Golgi Network Vesicle Budding pathway
REACT_234979
Clathrin derived vesicle budding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A5D7S0
UniProt Splice Variant
Entrez Gene 782742
UniGene Bt.5779 Bt.88260
RefSeq NM_001192487 XM_003583447
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC140660 DAAA02047419
GenPept AAI40661
RNA Seq Atlas 518407 782742

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca