InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: TPI1

Summary

InnateDB Gene

IDBG-640193.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TPI1

Gene Name

Triosephosphate isomerase

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000019782

Encoded Proteins

IDBP-692425

Triosephosphate isomerase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111669:
This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:103942403-103945759

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000026358

ENSBTAP00000026358

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.

Predicted by orthology
Total	30 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004807	triose-phosphate isomerase activity
GO:0005515	protein binding
GO:0016853	isomerase activity

Biological Process

GO:0006006	glucose metabolic process
GO:0006094	gluconeogenesis
GO:0006096	glycolytic process
GO:0006098	pentose-phosphate shunt
GO:0007275	multicellular organismal development
GO:0008152	metabolic process
GO:0019682	glyceraldehyde-3-phosphate metabolic process