InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: OPRL1

Summary

InnateDB Gene

IDBG-640397.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

OPRL1

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000045701

Encoded Proteins

IDBP-692652

opiate receptor-like 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125510:
The protein encoded by this gene is a G protein-coupled receptor whose expression can be induced by phytohemagglutinin. The encoded integral membrane protein is a receptor for the 17 aa neuropeptide nociceptin/orphanin FQ. This gene may be involved in the regulation of numerous brain activities, particularly instinctive and emotional behaviors. A promoter for this gene also functions as a promoter for another gene, regulator of G-protein signalling 19 (RGS19), located on the opposite strand. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 13:54254093-54255011

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000063812

ENSBTAP00000055794

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001626	nociceptin receptor activity
GO:0004871	signal transducer activity
GO:0004930	G-protein coupled receptor activity
GO:0004985	opioid receptor activity
GO:0005515	protein binding

Biological Process

GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007204	positive regulation of cytosolic calcium ion concentration
GO:0019233	sensory perception of pain
GO:0038003	opioid receptor signaling pathway