InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: RAPGEF4

Summary

InnateDB Gene

IDBG-640564.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RAPGEF4

Gene Name

rap guanine nucleotide exchange factor 4

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000020984

Encoded Proteins

IDBP-692860

Rap guanine nucleotide exchange factor (GEF) 4

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000091428:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:23644876-23974945

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000061074

ENSBTAP00000053320

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005085	guanyl-nucleotide exchange factor activity
GO:0005088	Ras guanyl-nucleotide exchange factor activity
GO:0005515	protein binding
GO:0008603	cAMP-dependent protein kinase regulator activity
GO:0017016	Ras GTPase binding
GO:0030552	cAMP binding

Biological Process

GO:0001932	regulation of protein phosphorylation
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0017156	calcium ion-dependent exocytosis
GO:0017157	regulation of exocytosis
GO:0019933	cAMP-mediated signaling
GO:0030073	insulin secretion
GO:0032318	regulation of Ras GTPase activity
GO:0035556	intracellular signal transduction
GO:0043087	regulation of GTPase activity
GO:0043547	positive regulation of GTPase activity
GO:0045859	regulation of protein kinase activity
GO:0051056	regulation of small GTPase mediated signal transduction