InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: MYH14

Summary

InnateDB Gene

IDBG-640934.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MYH14

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000002580

Encoded Proteins

IDBP-693291

myosin, heavy chain 14, non-muscle

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105357:
This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-14 (MYO14). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene result in one form of autosomal dominant hearing impairment. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 18:56874763-56947774

Strand

Forward strand

Band

Transcripts

ENSBTAT00000003343

ENSBTAP00000003343

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000146	microfilament motor activity
GO:0000166	nucleotide binding
GO:0003774	motor activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0030898	actin-dependent ATPase activity
GO:0051015	actin filament binding

Biological Process

GO:0003009	skeletal muscle contraction
GO:0006200	ATP catabolic process
GO:0007519	skeletal muscle tissue development
GO:0007605	sensory perception of sound
GO:0008152	metabolic process
GO:0014732	skeletal muscle atrophy
GO:0019228	neuronal action potential
GO:0030048	actin filament-based movement
GO:0031032	actomyosin structure organization
GO:0070584	mitochondrion morphogenesis
GO:0071625	vocalization behavior

Cellular Component

GO:0001725	stress fiber
GO:0005737	cytoplasm
GO:0016020	membrane
GO:0016459	myosin complex
GO:0016460	myosin II complex
GO:0030424	axon
GO:0030426	growth cone
GO:0042641	actomyosin
GO:0070062	extracellular vesicular exosome
GO:0097513	myosin II filament