InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: KCNC3

Summary

InnateDB Gene

IDBG-640985.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KCNC3

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000039935

Encoded Proteins

IDBP-693295

potassium voltage-gated channel, Shaw-related subfamily, member 3

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000131398:
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. [provided by RefSeq, Jul 2008]
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Alternate splicing results in several transcript variants. [provided by RefSeq, Mar 2014]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 18:56952428-56963679

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000020819

ENSBTAP00000020819

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005244	voltage-gated ion channel activity
GO:0005249	voltage-gated potassium channel activity
GO:0005251	delayed rectifier potassium channel activity
GO:0005267	potassium channel activity
GO:0005525	GTP binding

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0006813	potassium ion transport
GO:0034765	regulation of ion transmembrane transport
GO:0046928	regulation of neurotransmitter secretion
GO:0051260	protein homooligomerization
GO:0055085	transmembrane transport
GO:0071805	potassium ion transmembrane transport

Cellular Component

GO:0008076	voltage-gated potassium channel complex
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030673	axolemma
GO:0031594	neuromuscular junction
GO:0032590	dendrite membrane
GO:0032809	neuronal cell body membrane
GO:0043679	axon terminus

Orthologs

Species

Homo sapiens

Mus musculus

Gene ID

Gene Order

ENSG00000131398

View Gene Order

ENSMUSG00000062785

View Gene Order

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

REACT_75770

Voltage gated Potassium channels pathway

REACT_13685

Neuronal System pathway

REACT_75908

Potassium Channels pathway

KEGG

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

E1BC13

UniProt Splice Variant

Entrez Gene

617852

UniGene

RefSeq

HUGO

HGNC:6235

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02047493 DAAA02047494 DAAA02047495 DAAA02047496

GenPept

RNA Seq Atlas

617852