Version 5.4
Bos taurus Gene: BT.33843
Summary
InnateDB Gene IDBG-640988.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.33843
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000006780
Encoded Proteins
IDBP-693311
Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000131400:
The activation peptides of aspartic proteinases plays role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A gene is expressed predominantly in lung and kidney. Its translation product is predicted to be a fully functional, glycosylated aspartic proteinase precursor containing an RGD motif and an additional 18 residues at its C-terminus. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:56967043-56974391
Strand Reverse strand
Band
Transcripts
ENSBTAT00000008917 ENSBTAP00000008917
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004175 endopeptidase activity
GO:0004190 aspartic-type endopeptidase activity
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006508 proteolysis
GO:0033619 membrane protein proteolysis
GO:0043129 surfactant homeostasis
Cellular Component
GO:0005615 extracellular space
GO:0005764 lysosome
GO:0070062 extracellular vesicular exosome
GO:0097208 alveolar lamellar body
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000131400
View Gene Order
ENSMUSG00000002204
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04142
Lysosome pathway
mmu04142
Lysosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BJW6
UniProt Splice Variant
Entrez Gene 539259
UniGene Bt.33843
RefSeq XM_001790617 XM_002695127
HUGO HGNC:13395
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02047496
GenPept
RNA Seq Atlas 539259

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca