| Bos taurus Gene: AP1M1 | |||||||||||||
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| Summary | |||||||||||||
| InnateDB Gene | IDBG-642302.3 | ||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
| Gene Symbol | AP1M1 | ||||||||||||
| Gene Name | AP-1 complex subunit mu-1 | ||||||||||||
| Synonyms | |||||||||||||
| Species | Bos taurus | ||||||||||||
| Ensembl Gene | ENSBTAG00000013329 | ||||||||||||
| Encoded Proteins | 
                                    
                                    
                                     
                                            
                                            AP-1 complex subunit mu-1 
                                            
                                         
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| Protein Structure | 
                                     
                                         
                                         
                                         
                                         
                                         
                                         
                                         
                                         
                                         
                                         
                                        
                                    
                                                              
                                         
                                         
                                         
                                         
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
| Entrez Gene | |||||||||||||
| Summary | 
                                    
                                    
                                    This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000072958:
 The protein encoded by this gene is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. The other components of this complex are beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1. This complex is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]  | 
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| Gene Information | |||||||||||||
| Type | Protein coding | ||||||||||||
| Genomic Location | Chromosome 7:7820650-7850254 | ||||||||||||
| Strand | Reverse strand | ||||||||||||
| Band | |||||||||||||
| Transcripts | 
                                    
                                    
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| Interactions | |||||||||||||
| Number of Interactions | 
                                    This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
                                    
                                     They are also associated with 18 interaction(s) predicted by orthology. 
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| Gene Ontology | |||||||||||||
Molecular Function  | 
                                
                                    
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| Biological Process | 
                                    
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| Cellular Component | 
                                    
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| Orthologs | |||||||||||||
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                                     Species 
                                    
                                            Homo sapiens 
                                    
                                            Mus musculus 
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                                     Gene ID 
                                        Gene Order 
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| Pathways | |||||||||||||
| NETPATH | |||||||||||||
| REACTOME | 
                                    
                                     Golgi Associated Vesicle Biogenesis pathway 
                                    Immune System pathway 
                                    Clathrin derived vesicle budding pathway 
                                    MHC class II antigen presentation pathway 
                                    trans-Golgi Network Vesicle Budding pathway 
                                    Adaptive Immune System pathway 
                                    Lysosome Vesicle Biogenesis pathway 
                                    Membrane Trafficking pathway 
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| KEGG | |||||||||||||
| INOH | |||||||||||||
| PID NCI | |||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||
| NETPATH | |||||||||||||
| REACTOME | 
                                    
                                    
                                     MHC class II antigen presentation pathway 
                                    Nef mediated downregulation of MHC class I complex cell surface expression pathway 
                                    Lysosome Vesicle Biogenesis pathway 
                                    Golgi Associated Vesicle Biogenesis pathway 
                                    Clathrin derived vesicle budding pathway 
                                    trans-Golgi Network Vesicle Budding pathway 
                                    Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters pathway 
                                    Adaptive Immune System pathway 
                                    Immune System pathway 
                                    HIV Infection pathway 
                                    The role of Nef in HIV-1 replication and disease pathogenesis pathway 
                                    Host Interactions of HIV factors pathway 
                                    Disease pathway 
                                    Membrane Trafficking pathway 
                                    Membrane Trafficking pathway 
                                    Lysosome Vesicle Biogenesis pathway 
                                    Immune System pathway 
                                    Golgi Associated Vesicle Biogenesis pathway 
                                    MHC class II antigen presentation pathway 
                                    trans-Golgi Network Vesicle Budding pathway 
                                    Clathrin derived vesicle budding pathway 
                                    Adaptive Immune System pathway 
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| KEGG | 
                                    
                                     Lysosome pathway 
                                    Lysosome pathway 
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| INOH | |||||||||||||
| PID NCI | 
                                    
                                    
                                    
                                    
                                    
                                    
                                    
                                     E-cadherin signaling in the nascent adherens junction 
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| Cross-References | |||||||||||||
| SwissProt | Q2KJ81 | ||||||||||||
| TrEMBL | |||||||||||||
| UniProt Splice Variant | |||||||||||||
| Entrez Gene | 504310 | ||||||||||||
| UniGene | Bt.23352 | ||||||||||||
| RefSeq | NM_001045884 XM_005208484 XM_005208485 | ||||||||||||
| HUGO | |||||||||||||
| OMIM | |||||||||||||
| CCDS | |||||||||||||
| HPRD | |||||||||||||
| IMGT | |||||||||||||
| EMBL | BC105477 | ||||||||||||
| GenPept | AAI05478 | ||||||||||||
| RNA Seq Atlas | 504310 | ||||||||||||