Version 5.4
Bos taurus Gene: ALB
Summary
InnateDB Gene IDBG-642992.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ALB
Gene Name Serum albumin
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000017121
Encoded Proteins
IDBP-695510
serum albumin precursor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163631:
Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:90232762-90251126
Strand Forward strand
Band
Transcripts
ENSBTAT00000022763 ENSBTAP00000022763
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 128 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 128 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005504 fatty acid binding
GO:0005515 protein binding
GO:0008144 drug binding
GO:0008289 lipid binding
GO:0015643 toxic substance binding
GO:0019825 oxygen binding
GO:0030170 pyridoxal phosphate binding
GO:0046872 metal ion binding
GO:0051087 chaperone binding
Biological Process
GO:0001895 retina homeostasis
GO:0006810 transport
GO:0009267 cellular response to starvation
GO:0019836 hemolysis by symbiont of host erythrocytes
GO:0043066 negative regulation of apoptotic process
GO:0051659 maintenance of mitochondrion location
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0043234 protein complex
GO:0070062 extracellular vesicular exosome
GO:0072562 blood microparticle
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000163631
View Gene Order
ENSMUSG00000029368
View Gene Order
Pathways
NETPATH
REACTOME
REACT_202252
Platelet degranulation pathway
REACT_222460
SLC-mediated transmembrane transport pathway
REACT_216574
Transport of organic anions pathway
REACT_212432
Lipoprotein metabolism pathway
REACT_223874
Recycling of bile acids and salts pathway
REACT_212196
Hemostasis pathway
REACT_209572
Platelet activation, signaling and aggregation pathway
REACT_223103
Transmembrane transport of small molecules pathway
REACT_212308
Response to elevated platelet cytosolic Ca2+ pathway
REACT_222480
HDL-mediated lipid transport pathway
REACT_218813
Transport of vitamins, nucleosides, and related molecules pathway
REACT_213817
Binding and Uptake of Ligands by Scavenger Receptors pathway
REACT_219933
Metabolism of lipids and lipoproteins pathway
REACT_223789
Bile acid and bile salt metabolism pathway
REACT_219139
Metabolism pathway
REACT_219679
Scavenging of heme from plasma pathway
REACT_213267
Lipid digestion, mobilization, and transport pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
REACT_160163
Scavenging of heme from plasma pathway
REACT_318
Platelet degranulation pathway
REACT_1280
Response to elevated platelet cytosolic Ca2+ pathway
REACT_23988
Transport of organic anions pathway
REACT_22285
Transport of vitamins, nucleosides, and related molecules pathway
REACT_11042
Recycling of bile acids and salts pathway
REACT_13621
HDL-mediated lipid transport pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_11040
Bile acid and bile salt metabolism pathway
REACT_798
Platelet activation, signaling and aggregation pathway
REACT_160300
Binding and Uptake of Ligands by Scavenger Receptors pathway
REACT_6823
Lipoprotein metabolism pathway
REACT_111217
Metabolism pathway
REACT_602
Lipid digestion, mobilization, and transport pathway
REACT_19118
SLC-mediated transmembrane transport pathway
REACT_604
Hemostasis pathway
REACT_230203
Platelet degranulation pathway
REACT_224553
Hemostasis pathway
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_232951
Transport of vitamins, nucleosides, and related molecules pathway
REACT_239346
Recycling of bile acids and salts pathway
REACT_213857
HDL-mediated lipid transport pathway
REACT_188937
Metabolism pathway
REACT_224879
Platelet activation, signaling and aggregation pathway
REACT_196575
Scavenging of heme from plasma pathway
REACT_196573
Binding and Uptake of Ligands by Scavenger Receptors pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_238381
Lipid digestion, mobilization, and transport pathway
REACT_211709
Lipoprotein metabolism pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_210189
Transport of organic anions pathway
REACT_206166
Response to elevated platelet cytosolic Ca2+ pathway
REACT_229469
Bile acid and bile salt metabolism pathway
KEGG
INOH
PID NCI
hnf3bpathway
FOXA2 and FOXA3 transcription factor networks
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.106669
RefSeq NM_180992
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca