InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: DGKQ

Summary

InnateDB Gene

IDBG-643811.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DGKQ

Gene Name

diacylglycerol kinase theta

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000017240

Encoded Proteins

IDBP-696419

diacylglycerol kinase, theta 110kDa

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000145214:
The protein encoded by this gene contains three cysteine-rich domains, a proline-rich region, and a pleckstrin homology domain with an overlapping Ras-associating domain. It is localized in the speckle domains of the nucleus, and mediates the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 6:109057364-109077151

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000022905

ENSBTAP00000022905

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003951	NAD+ kinase activity
GO:0004143	diacylglycerol kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0019900	kinase binding
GO:0033613	activating transcription factor binding
GO:0043274	phospholipase binding

Biological Process

GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0008152	metabolic process
GO:0016310	phosphorylation
GO:0019933	cAMP-mediated signaling
GO:0033198	response to ATP
GO:0035556	intracellular signal transduction
GO:0070493	thrombin receptor signaling pathway
GO:0070528	protein kinase C signaling