Bos taurus Gene: BT.18280
Summary
InnateDB Gene IDBG-643872.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.18280
Gene Name spondin-2 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004261
Encoded Proteins
spondin-2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
[Homo sapiens] SPON2 expression is upregulated during intestinal inflammation and may induce NF-kappaB promoter activation in a TLR-9 mediated manner.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000159674:
Gene Information
Type Protein coding
Genomic Location Chromosome 6:109224627-109228237
Strand Reverse strand
Band
Transcripts
ENSBTAT00000005582 ENSBTAP00000005582
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001530 lipopolysaccharide binding
GO:0003823 antigen binding
GO:0005515 protein binding
Biological Process
GO:0002448 mast cell mediated immunity
GO:0008228 opsonization
GO:0032496 response to lipopolysaccharide
GO:0032755 positive regulation of interleukin-6 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0042742 defense response to bacterium
GO:0043152 induction of bacterial agglutination
GO:0045087 innate immune response
GO:0050832 defense response to fungus
GO:0051607 defense response to virus
GO:0060907 positive regulation of macrophage cytokine production
GO:0071222 cellular response to lipopolysaccharide
Cellular Component
GO:0005615 extracellular space
GO:0031012 extracellular matrix
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Post-translational protein modification pathway
O-linked glycosylation pathway
Metabolism of proteins pathway
O-glycosylation of TSR domain-containing proteins pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Beta2 integrin cell surface interactions
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.18280
RefSeq NM_001046157
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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