Bos taurus Gene: BT.36811 | |||||||||||||||
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Summary | |||||||||||||||
InnateDB Gene | IDBG-644126.3 | ||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
Gene Symbol | BT.36811 | ||||||||||||||
Gene Name | arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 | ||||||||||||||
Synonyms | DDEF1 | ||||||||||||||
Species | Bos taurus | ||||||||||||||
Ensembl Gene | ENSBTAG00000003185 | ||||||||||||||
Encoded Proteins |
arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
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Protein Structure | |||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||
Entrez Gene | |||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000153317:
This gene encodes an ADP-ribosylation factor (ARF) GTPase-activating protein. The GTPase-activating activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2), and is greater towards ARF1 and ARF5, and lesser for ARF6. This gene maybe involved in regulation of membrane trafficking and cytoskeleton remodeling. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
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Gene Information | |||||||||||||||
Type | Protein coding | ||||||||||||||
Genomic Location | Chromosome 14:11327981-11696284 | ||||||||||||||
Strand | Forward strand | ||||||||||||||
Band | |||||||||||||||
Transcripts |
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Interactions | |||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 46 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||
NETPATH |
EGFR1 pathway
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REACTOME | |||||||||||||||
KEGG |
Fc gamma R-mediated phagocytosis pathway
Endocytosis pathway
Fc gamma R-mediated phagocytosis pathway
Endocytosis pathway
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INOH | |||||||||||||||
PID NCI |
Signaling events mediated by focal adhesion kinase
Arf1 pathway
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Cross-References | |||||||||||||||
SwissProt | |||||||||||||||
TrEMBL | E1B7Z1 | ||||||||||||||
UniProt Splice Variant | |||||||||||||||
Entrez Gene | 327705 | ||||||||||||||
UniGene | Bt.36811 | ||||||||||||||
RefSeq | NM_175821 | ||||||||||||||
HUGO | |||||||||||||||
OMIM | |||||||||||||||
CCDS | |||||||||||||||
HPRD | |||||||||||||||
IMGT | |||||||||||||||
EMBL | DAAA02037608 DAAA02037609 DAAA02037610 DAAA02037611 DAAA02037612 DAAA02037613 DAAA02037614 DAAA02037615 DAAA02037616 DAAA02037617 | ||||||||||||||
GenPept | |||||||||||||||
RNA Seq Atlas | 327705 | ||||||||||||||