Bos taurus Gene: CDC42EP2
Summary
InnateDB Gene IDBG-644168.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDC42EP2
Gene Name Cdc42 effector protein 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000032089
Encoded Proteins
Cdc42 effector protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149798:
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 29:44189278-44195090
Strand Forward strand
Band
Transcripts
ENSBTAT00000045518 ENSBTAP00000042899
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001515 opioid peptide activity
GO:0005100 Rho GTPase activator activity
GO:0005515 protein binding
GO:0017049 GTP-Rho binding
Biological Process
GO:0008360 regulation of cell shape
GO:0030036 actin cytoskeleton organization
GO:0030838 positive regulation of actin filament polymerization
GO:0031274 positive regulation of pseudopodium assembly
GO:0032321 positive regulation of Rho GTPase activity
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0012505 endomembrane system
GO:0015630 microtubule cytoskeleton
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q08DN6
TrEMBL
UniProt Splice Variant
Entrez Gene 507966
UniGene Bt.52103
RefSeq NM_001075341 XM_005227025
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC123647
GenPept AAI23648
RNA Seq Atlas 507966
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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