InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: PIP5K1C

Summary

InnateDB Gene

IDBG-644378.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PIP5K1C

Gene Name

phosphatidylinositol-4-phosphate 5-kinase type-1 gamma

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000000710

Encoded Proteins

IDBP-697023

phosphatidylinositol-4-phosphate 5-kinase, type I, gamma

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000186111:
This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase. The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate. This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration. Mutations at this locus have been associated with lethal congenital contractural syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Sep 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 7:21514211-21535516

Strand

Forward strand

Band

Transcripts

ENSBTAT00000061402

ENSBTAP00000053438

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0016307	phosphatidylinositol phosphate kinase activity
GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:1990147	talin binding

Biological Process

GO:0007016	cytoskeletal anchoring at plasma membrane
GO:0007409	axonogenesis
GO:0046488	phosphatidylinositol metabolic process
GO:0046854	phosphatidylinositol phosphorylation
GO:0070527	platelet aggregation