Bos taurus Gene: RAD21 | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-644888.3 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | RAD21 | ||||||||||||||||||
Gene Name | Double-strand-break repair protein rad21 homolog | ||||||||||||||||||
Synonyms | |||||||||||||||||||
Species | Bos taurus | ||||||||||||||||||
Ensembl Gene | ENSBTAG00000007303 | ||||||||||||||||||
Encoded Proteins |
Double-strand-break repair protein rad21 homolog
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
InnateDB Annotation from Orthologs | |||||||||||||||||||
Summary |
[Homo sapiens] RAD21 is part of the cohesin complex which is the cellular machinery involved in sister chromatid cohesion and that which requires access to the nucleosomal DNA to perform its function in chromosome segregation.
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Entrez Gene | |||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164754:
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 14:49558483-49588327 | ||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||
Band | |||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 212 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathways | |||||||||||||||||||
NETPATH | |||||||||||||||||||
REACTOME |
S Phase pathway
Cohesin Loading onto Chromatin pathway
Meiotic synapsis pathway
Mitotic Telophase/Cytokinesis pathway
M Phase pathway
Separation of Sister Chromatids pathway
Meiosis pathway
Mitotic Metaphase and Anaphase pathway
Mitotic Anaphase pathway
Cell Cycle, Mitotic pathway
Cell Cycle pathway
Establishment of Sister Chromatid Cohesion pathway
Resolution of Sister Chromatid Cohesion pathway
Mitotic Prometaphase pathway
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KEGG | |||||||||||||||||||
INOH | |||||||||||||||||||
PID NCI | |||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||
NETPATH | |||||||||||||||||||
REACTOME |
Meiotic synapsis pathway
Resolution of Sister Chromatid Cohesion pathway
Mitotic Prometaphase pathway
Separation of Sister Chromatids pathway
Cohesin Loading onto Chromatin pathway
Mitotic Telophase/Cytokinesis pathway
Establishment of Sister Chromatid Cohesion pathway
S Phase pathway
Cell Cycle pathway
M Phase pathway
Mitotic Anaphase pathway
Cell Cycle, Mitotic pathway
Meiosis pathway
Mitotic Metaphase and Anaphase pathway
Meiotic Synapsis pathway
Mus musculus biological processes pathway
Cell Cycle, Mitotic pathway
Separation of Sister Chromatids pathway
Resolution of Sister Chromatid Cohesion pathway
Meiotic synapsis pathway
Cell Cycle pathway
M Phase pathway
Mitotic Telophase/Cytokinesis pathway
Mitotic Metaphase and Anaphase pathway
Mitotic Prometaphase pathway
Cohesin Loading onto Chromatin pathway
Establishment of Sister Chromatid Cohesion pathway
Meiosis pathway
Mitotic Anaphase pathway
S Phase pathway
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KEGG |
Cell cycle pathway
Cell cycle pathway
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INOH | |||||||||||||||||||
PID NCI | |||||||||||||||||||
Cross-References | |||||||||||||||||||
SwissProt | Q3SWX9 | ||||||||||||||||||
TrEMBL | |||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | 540966 | ||||||||||||||||||
UniGene | Bt.15668 Bt.85235 | ||||||||||||||||||
RefSeq | NM_001034717 | ||||||||||||||||||
HUGO | |||||||||||||||||||
OMIM | |||||||||||||||||||
CCDS | |||||||||||||||||||
HPRD | |||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | BC104612 | ||||||||||||||||||
GenPept | AAI04613 | ||||||||||||||||||
RNA Seq Atlas | 540966 | ||||||||||||||||||