Bos taurus Gene: DNASE1L3
Summary
InnateDB Gene IDBG-645218.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DNASE1L3
Gene Name deoxyribonuclease gamma precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000018294
Encoded Proteins
deoxyribonuclease I-like 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163687:
This gene encodes a member of the deoxyribonuclease I family. The encoded protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Mutations in this gene are a cause of systemic lupus erythematosus-16. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:43639336-43658740
Strand Forward strand
Band
Transcripts
ENSBTAT00000024347 ENSBTAP00000024347
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004519 endonuclease activity
GO:0004536 deoxyribonuclease activity
GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters
Biological Process
GO:0006308 DNA catabolic process
GO:0006309 apoptotic DNA fragmentation
GO:0010623 developmental programmed cell death
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt
TrEMBL F1MGQ1
UniProt Splice Variant
Entrez Gene 784519
UniGene Bt.856
RefSeq NM_001205724 XM_001789758
HUGO HGNC:2959
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02054297
GenPept
RNA Seq Atlas 512512 784519