Bos taurus Gene: HTR4
Summary
InnateDB Gene IDBG-646216.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HTR4
Gene Name 5-hydroxytryptamine receptor 4
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000010837
Encoded Proteins
5-hydroxytryptamine receptor 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164270:
This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:61907647-62066996
Strand Reverse strand
Band
Transcripts
ENSBTAT00000014383 ENSBTAP00000014383
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0004930 G-protein coupled receptor activity
GO:0004993 serotonin receptor activity
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007268 synaptic transmission
GO:0008284 positive regulation of cell proliferation
GO:0032098 regulation of appetite
Cellular Component
GO:0005737 cytoplasm
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
G alpha (s) signalling events pathway
Serotonin receptors pathway
Amine ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
G alpha (s) signalling events pathway
GPCR downstream signaling pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
Amine ligand-binding receptors pathway
Serotonin receptors pathway
GPCR ligand binding pathway
Signal Transduction pathway
KEGG
Neuroactive ligand-receptor interaction pathway
Calcium signaling pathway pathway
Calcium signaling pathway pathway
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1N3N9
UniProt Splice Variant
Entrez Gene 317708
UniGene Bt.12807
RefSeq NM_001040485
HUGO HGNC:5299
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02020592 DAAA02020593
GenPept
RNA Seq Atlas 317708