Version 5.4
Bos taurus Gene: RPN1
Summary
InnateDB Gene IDBG-646499.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RPN1
Gene Name dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000005191
Encoded Proteins
IDBP-699312
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163902:
This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein forms part of the regulatory subunit of the 26S proteasome and may mediate binding of ubiquitin-like domains to this proteasome. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:59952594-59965985
Strand Forward strand
Band
Transcripts
ENSBTAT00000006847 ENSBTAP00000006847
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 48 interaction(s) predicted by orthology.
Predicted by orthology
Total 48 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity
Biological Process
GO:0006486 protein glycosylation
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000163902
View Gene Order
ENSMUSG00000030062
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22426
Asparagine N-linked glycosylation pathway
REACT_115902
SRP-dependent cotranslational protein targeting to membrane pathway
REACT_22161
Post-translational protein modification pathway
REACT_1014
Translation pathway
REACT_17015
Metabolism of proteins pathway
REACT_71
Gene Expression pathway
REACT_254308
Translation pathway
REACT_247926
Metabolism of proteins pathway
REACT_196445
SRP-dependent cotranslational protein targeting to membrane pathway
REACT_233572
Gene Expression pathway
KEGG
hsa00510
N-Glycan biosynthesis pathway
hsa04141
Protein processing in endoplasmic reticulum pathway
mmu00510
N-Glycan biosynthesis pathway
mmu04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.62599
RefSeq NM_001082605
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca