Version 5.4
Homo sapiens Gene: CLEC11A
Summary
InnateDB Gene IDBG-64750.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLEC11A
Gene Name C-type lectin domain family 11, member A
Synonyms CLECSF3; LSLCL; P47; SCGF
Species Homo sapiens
Ensembl Gene ENSG00000105472
Encoded Proteins
IDBP-64752
C-type lectin domain family 11, member A
IDBP-759999
IDBP-808175
C-type lectin domain family 11, member A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:50723329-50725718
Strand Forward strand
Band q13.33
Transcripts
ENST00000250340 ENSP00000250340
ENST00000599973 ENSP00000471075
ENST00000617718 ENSP00000480599
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008083 growth factor activity
GO:0030246 carbohydrate binding
Biological Process
GO:0008284 positive regulation of cell proliferation
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000004473
View Gene Order
ENSBTAG00000005576
Not yet available
Cross-References
SwissProt Q9Y240
TrEMBL
UniProt Splice Variant
Entrez Gene 6320
UniGene Hs.512680
RefSeq NM_002975
HUGO HGNC:10576
OMIM 604713
CCDS CCDS12800
HPRD 05277
IMGT
EMBL AB009244 AF020044 AF087658 AK314141 BC005810 CH471135
GenPept AAC39569 AAD26533 AAH05810 BAA32404 BAG36831 EAW71896
RNA Seq Atlas 6320

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca