Version 5.4
Homo sapiens Gene: TRIM39
Summary
InnateDB Gene IDBG-75923.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRIM39
Gene Name tripartite motif containing 39
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000204599
Encoded Proteins
IDBP-75927
tripartite motif containing 39
IDBP-75929
tripartite motif containing 39
IDBP-237260
tripartite motif containing 39
IDBP-237262
tripartite motif containing 39
IDBP-237264
tripartite motif containing 39
IDBP-368528
tripartite motif containing 39
IDBP-368532
tripartite motif containing 39
IDBP-368538
tripartite motif containing 39
IDBP-368565
tripartite motif containing 39
IDBP-368568
tripartite motif containing 39
IDBP-368573
tripartite motif containing 39
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This locus represents naturally occurring read-through transcription between the neighboring TRIM39 (tripartite motif-containing 39) and RPP21 (ribonuclease P/MRP 21kDa subunit) genes on chromosome 6. The read-through transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Nov 2010] The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified. This gene lies within the major histocompatibility complex class I region on chromosome 6. Alternate splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:30326479-30343729
Strand Forward strand
Band p22.1
Transcripts
ENST00000376656 ENSP00000365844
ENST00000376659 ENSP00000365847
ENST00000396551 ENSP00000379800
ENST00000396548 ENSP00000379797
ENST00000396547 ENSP00000379796
ENST00000458516 ENSP00000405928
ENST00000440271 ENSP00000394768
ENST00000428728 ENSP00000406019
ENST00000428404 ENSP00000405498
ENST00000428555 ENSP00000397952
ENST00000420746 ENSP00000388224
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 54 experimentally validated interaction(s) in this database.
Experimentally validated
Total 54 [view]
Protein-Protein 53 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006915 apoptotic process
GO:0016567 protein ubiquitination
GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:2001235 positive regulation of apoptotic signaling pathway
Cellular Component
GO:0005622 intracellular
GO:0005739 mitochondrion
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000045409
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.413493
RefSeq NM_021253 NM_172016
HUGO
OMIM
CCDS CCDS34377 CCDS34378
HPRD 09298
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca