Version 5.4
Homo sapiens Gene: CDX4
Summary
InnateDB Gene IDBG-77107.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDX4
Gene Name caudal type homeobox 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000131264
Encoded Proteins
IDBP-77109
caudal type homeobox 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of a small subfamily of homeobox containing transcription factors. The encoded protein may regulate homeobox gene expression during anteroposterior patterning and hematopoiesis. [provided by RefSeq, Aug 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome X:73447254-73455245
Strand Forward strand
Band q13.2
Transcripts
ENST00000373514 ENSP00000362613
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001568 blood vessel development
GO:0001890 placenta development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organismal development
GO:0009952 anterior/posterior pattern specification
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0060711 labyrinthine layer development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031326
View Gene Order
ENSBTAG00000001726
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
betacatenin_nuc_pathway
Regulation of nuclear beta catenin signaling and target gene transcription
Cross-References
SwissProt O14627
TrEMBL
UniProt Splice Variant
Entrez Gene 1046
UniGene Hs.553488
RefSeq NM_005193
HUGO HGNC:1808
OMIM 300025
CCDS CCDS14424
HPRD
IMGT
EMBL AF003530 AF029877 AF029878 AF029879 AL450108 BC128233 CH471104
GenPept AAB66319 AAD01894 AAI28234 CAI40795 EAW98667
RNA Seq Atlas 1046

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca