Version 5.4
Homo sapiens Gene: TCEAL1
Summary
InnateDB Gene IDBG-80749.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TCEAL1
Gene Name transcription elongation factor A (SII)-like 1
Synonyms p21; pp21; SIIR; WEX9
Species Homo sapiens
Ensembl Gene ENSG00000172465
Encoded Proteins
IDBP-80751
transcription elongation factor A (SII)-like 1
IDBP-80755
transcription elongation factor A (SII)-like 1
IDBP-80757
transcription elongation factor A (SII)-like 1
IDBP-810382
transcription elongation factor A (SII)-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. The encoded protein is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:103628704-103630953
Strand Forward strand
Band q22.2
Transcripts
ENST00000372626 ENSP00000361709
ENST00000372625 ENSP00000361708
ENST00000372624 ENSP00000361707
ENST00000469820
ENST00000619397 ENSP00000484298
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
Experimentally validated
Total 22 [view]
Protein-Protein 22 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000049536
View Gene Order
ENSBTAG00000008485
Not yet available
Cross-References
SwissProt Q15170
TrEMBL
UniProt Splice Variant
Entrez Gene 9338
UniGene Hs.605138 Hs.95243
RefSeq NM_001006639 NM_004780 NM_001006640
HUGO HGNC:11616
OMIM 300237
CCDS CCDS35358
HPRD 02211
IMGT
EMBL AF095906 AL049610 BC000809 M99701
GenPept AAA60149 AAD17840 AAH00809 CAB55700
RNA Seq Atlas 9338

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca