Homo sapiens Gene: PDLIM1
Summary
InnateDB Gene IDBG-83349.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDLIM1
Gene Name PDZ and LIM domain 1
Synonyms CLIM1; CLP-36; CLP36; hCLIM1; HEL-S-112;
Species Homo sapiens
Ensembl Gene ENSG00000107438
Encoded Proteins
PDZ and LIM domain 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the enigma protein family. The protein contains two protein interacting domains, a PDZ domain at the amino terminal end and one to three LIM domains at the carboxyl terminal. It is a cytoplasmic protein associated with the cytoskeleton. The protein may function as an adapter to bring other LIM-interacting proteins to the cytoskeleton. Pseudogenes associated with this gene are located on chromosomes 3, 14 and 17. [provided by RefSeq, Oct 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:95237572-95291024
Strand Reverse strand
Band q23.33
Transcripts
ENST00000329399 ENSP00000360305
ENST00000492511
ENST00000477757
ENST00000490391
ENST00000493949
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 25 [view]
Protein-Protein 25 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0001666 response to hypoxia
GO:0006355 regulation of transcription, DNA-templated
GO:0006979 response to oxidative stress
Cellular Component
GO:0005667 transcription factor complex
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
EGFR1 pathway
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt O00151
TrEMBL V9HW92
UniProt Splice Variant
Entrez Gene 9124
UniGene
RefSeq NM_020992
HUGO HGNC:2067
OMIM 605900
CCDS CCDS7441
HPRD 09326
IMGT
EMBL AJ310549 AK314792 AL157834 AL160288 AY923052 BC000915 BC018755 CH471066 FJ224331 U90878
GenPept AAC05580 AAH00915 AAH18755 AAW82438 ACI46023 BAG37323 CAC32846 CAH70720 CAH72341 EAW50009
RNA Seq Atlas 9124