InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: LDB1

Summary

InnateDB Gene

IDBG-87759.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LDB1

Gene Name

LIM domain binding 1

Synonyms

CLIM2; NLI

Species

Homo sapiens

Ensembl Gene

ENSG00000198728

Encoded Proteins

IDBP-87761

LIM domain binding 1

IDBP-384825

LIM domain binding 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 10:102107560-102120453

Strand

Reverse strand

Band

q24.32

Transcripts

ENST00000361198	ENSP00000354616
ENST00000425280	ENSP00000392466
ENST00000461873
ENST00000490751

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
They are also associated with 46 interaction(s) predicted by orthology.

Experimentally validated
Total	32 [view]
Protein-Protein	31 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	46 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000989	transcription factor binding transcription factor activity
GO:0001102	RNA polymerase II activating transcription factor binding
GO:0001158	enhancer sequence-specific DNA binding
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003714	transcription corepressor activity
GO:0005515	protein binding
GO:0019899	enzyme binding
GO:0030274	LIM domain binding
GO:0042803	protein homodimerization activity
GO:0043621	protein self-association

Biological Process

GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
GO:0001702	gastrulation with mouth forming second
GO:0001942	hair follicle development
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006366	transcription from RNA polymerase II promoter
GO:0007275	multicellular organismal development
GO:0009948	anterior/posterior axis specification
GO:0010669	epithelial structure maintenance
GO:0016055	Wnt signaling pathway
GO:0021549	cerebellum development
GO:0021702	cerebellar Purkinje cell differentiation
GO:0022607	cellular component assembly
GO:0030182	neuron differentiation
GO:0032784	regulation of DNA-templated transcription, elongation
GO:0035019	somatic stem cell maintenance
GO:0043973	histone H3-K4 acetylation
GO:0045647	negative regulation of erythrocyte differentiation
GO:0045785	positive regulation of cell adhesion
GO:0045892	negative regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0046985	positive regulation of hemoglobin biosynthetic process
GO:0060322	head development

Cellular Component

GO:0000790	nuclear chromatin
GO:0005634	nucleus
GO:0005667	transcription factor complex
GO:0043234	protein complex

Orthologs

Species

Mus musculus

Bos taurus

Gene ID

Gene Order

ENSMUSG00000025223

View Gene Order

ENSBTAG00000005780

Not yet available

Pathways

NETPATH

REACTOME

KEGG

INOH

PID NCI

Cross-References

SwissProt

Q86U70

TrEMBL

UniProt Splice Variant

Entrez Gene

8861

UniGene

Hs.454418 Hs.735268

RefSeq

NM_003893 NM_001113407

HUGO

HGNC:6532

OMIM

603451

CCDS

CCDS7528 CCDS44472

HPRD

09144

IMGT

EMBL

AB016485 AB250384 AF064491 AF068652 AJ243098 AK300588 AL500527 BC000482 BC009246 BT007054

GenPept

AAC28341 AAC77818 AAH00482 AAH09246 AAP35703 BAA31991 BAE95402 BAG62286 CAB45409

RNA Seq Atlas

8861