Homo sapiens Gene: LDB1
Summary
InnateDB Gene IDBG-87759.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LDB1
Gene Name LIM domain binding 1
Synonyms CLIM2; NLI;
Species Homo sapiens
Ensembl Gene ENSG00000198728
Encoded Proteins
LIM domain binding 1
LIM domain binding 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 10:102107560-102120453
Strand Reverse strand
Band q24.32
Transcripts
ENST00000361198 ENSP00000354616
ENST00000425280 ENSP00000392466
ENST00000461873
ENST00000490751
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
They are also associated with 46 interaction(s) predicted by orthology.
Experimentally validated
Total 32 [view]
Protein-Protein 31 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 46 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000989 transcription factor binding transcription factor activity
GO:0001102 RNA polymerase II activating transcription factor binding
GO:0001158 enhancer sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003714 transcription corepressor activity
GO:0005515 protein binding
GO:0019899 enzyme binding
GO:0030274 LIM domain binding
GO:0042803 protein homodimerization activity
GO:0043621 protein self-association
Biological Process
GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
GO:0001702 gastrulation with mouth forming second
GO:0001942 hair follicle development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0007275 multicellular organismal development
GO:0009948 anterior/posterior axis specification
GO:0010669 epithelial structure maintenance
GO:0016055 Wnt signaling pathway
GO:0021549 cerebellum development
GO:0021702 cerebellar Purkinje cell differentiation
GO:0022607 cellular component assembly
GO:0030182 neuron differentiation
GO:0032784 regulation of DNA-templated transcription, elongation
GO:0035019 somatic stem cell maintenance
GO:0043973 histone H3-K4 acetylation
GO:0045647 negative regulation of erythrocyte differentiation
GO:0045785 positive regulation of cell adhesion
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0046985 positive regulation of hemoglobin biosynthetic process
GO:0060322 head development
Cellular Component
GO:0000790 nuclear chromatin
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0043234 protein complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
KEGG
INOH
PID BIOCARTA
Multi-step regulation of transcription by pitx2 [Biocarta view]
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.454418 Hs.735268
RefSeq NM_001113407 NM_003893
HUGO
OMIM
CCDS CCDS44472 CCDS7528
HPRD 09144
IMGT
EMBL
GenPept
RNA Seq Atlas