Version 5.4
Homo sapiens Gene: ELOVL5
Summary
InnateDB Gene IDBG-90996.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ELOVL5
Gene Name ELOVL fatty acid elongase 5
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000012660
Encoded Proteins
IDBP-90998
ELOVL fatty acid elongase 5
IDBP-91000
ELOVL fatty acid elongase 5
IDBP-91002
ELOVL fatty acid elongase 5
IDBP-598582
ELOVL fatty acid elongase 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary ELOVL5 plays a role in elongation of long-chain polyunsaturated fatty acids (Leonard et al., 2000 [PubMed 10970790]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:53267398-53349179
Strand Reverse strand
Band p12.1
Transcripts
ENST00000304434 ENSP00000306640
ENST00000370918 ENSP00000359956
ENST00000370913 ENSP00000359951
ENST00000485336
ENST00000465983
ENST00000486973
ENST00000542638 ENSP00000440728
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0009922 fatty acid elongase activity
Biological Process
GO:0006636 unsaturated fatty acid biosynthetic process
GO:0019432 triglyceride biosynthetic process
GO:0033559 unsaturated fatty acid metabolic process
GO:0034625 fatty acid elongation, monounsaturated fatty acid
GO:0034626 fatty acid elongation, polyunsaturated fatty acid
GO:0035338 long-chain fatty-acyl-CoA biosynthetic process
GO:0036109 alpha-linolenic acid metabolic process
GO:0042761 very long-chain fatty acid biosynthetic process
GO:0043651 linoleic acid metabolic process
GO:0044255 cellular lipid metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032349
View Gene Order
ENSBTAG00000003359
Not yet available
Pathways
NETPATH
REACTOME
REACT_121100
Linoleic acid (LA) metabolism pathway
REACT_121147
alpha-linolenic acid (ALA) metabolism pathway
REACT_380
Synthesis of very long-chain fatty acyl-CoAs pathway
REACT_1319
Fatty Acyl-CoA Biosynthesis pathway
REACT_1190
Triglyceride Biosynthesis pathway
REACT_22279
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121284
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa01040
Biosynthesis of unsaturated fatty acids pathway
hsa00062
Fatty acid elongation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.741463
RefSeq NM_001242828 NM_001242830 NM_001242831 NM_021814 XM_005249266 XM_005249267
HUGO
OMIM
CCDS CCDS4951 CCDS56433 CCDS56434 CCDS75470
HPRD 13268
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca