Version 5.4
Homo sapiens Gene: POLR3H
Summary
InnateDB Gene IDBG-9248.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POLR3H
Gene Name polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000100413
Encoded Proteins
IDBP-9250
polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
IDBP-9252
polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
IDBP-237366
polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
IDBP-293266
polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
IDBP-378122
polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
IDBP-378123
polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
IDBP-378127
polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 22:41525804-41544606
Strand Reverse strand
Band q13.2
Transcripts
ENST00000355209 ENSP00000347345
ENST00000337566 ENSP00000337627
ENST00000396504 ENSP00000379761
ENST00000407461 ENSP00000385315
ENST00000431534 ENSP00000395674
ENST00000432789 ENSP00000415053
ENST00000442616 ENSP00000408083
ENST00000420561
ENST00000483837
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
Experimentally validated
Total 26 [view]
Protein-Protein 26 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001056 RNA polymerase III activity
GO:0003677 DNA binding
GO:0003899 DNA-directed RNA polymerase activity
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0006351 transcription, DNA-templated
GO:0006383 transcription from RNA polymerase III promoter
GO:0006384 transcription initiation from RNA polymerase III promoter
GO:0006385 transcription elongation from RNA polymerase III promoter
GO:0006386 termination of RNA polymerase III transcription
GO:0010467 gene expression
GO:0032481 positive regulation of type I interferon production
GO:0045087 innate immune response
GO:0051607 defense response to virus
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005666 DNA-directed RNA polymerase III complex
GO:0005813 centrosome
GO:0005829 cytosol
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022476
View Gene Order
ENSBTAG00000005311
Not yet available
Pathways
NETPATH
REACTOME
REACT_22339
RNA Polymerase III Abortive And Retractive Initiation pathway
REACT_63
RNA Polymerase III Transcription Termination pathway
REACT_756
RNA Polymerase III Chain Elongation pathway
REACT_571
RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway
REACT_1036
RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway
REACT_347
RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway
REACT_281
RNA Polymerase III Transcription Initiation pathway
REACT_6802
Innate Immune System pathway
REACT_6900
Immune System pathway
REACT_1371
RNA Polymerase III Transcription pathway
REACT_21352
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_118823
Cytosolic sensors of pathogen-associated DNA pathway
REACT_71
Gene Expression pathway
KEGG
hsa00240
Pyrimidine metabolism pathway
hsa00230
Purine metabolism pathway
hsa03020
RNA polymerase pathway
hsa04623
Cytosolic DNA-sensing pathway pathway
INOH
PID NCI
Cross-References
SwissProt Q9Y535
TrEMBL A0A024R1P3 E7ERZ2 F8WDS5 F8WDV1 Q6ZPA8
UniProt Splice Variant
Entrez Gene 171568
UniGene Hs.712617
RefSeq NM_001018050 NM_001018052 NM_001282884 NM_001282885 NM_138338
HUGO HGNC:30349
OMIM
CCDS CCDS14018 CCDS33651
HPRD
IMGT
EMBL AB051452 AK129663 AL023553 AY092087 BC017248 BC088367 CH471095 CR456459
GenPept AAH17248 AAH88367 AAM18217 BAB33335 BAC85211 CAB46023 CAG30345 CAQ10207 EAW60437 EAW60438 EAW60439 EAW60440 EAW60441
RNA Seq Atlas 171568

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca