Homo sapiens Gene: PAOX
Summary
InnateDB Gene IDBG-93753.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PAOX
Gene Name polyamine oxidase (exo-N4-amino)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000148832
Encoded Proteins
polyamine oxidase (exo-N4-amino)
polyamine oxidase (exo-N4-amino)
polyamine oxidase (exo-N4-amino)
polyamine oxidase (exo-N4-amino)
polyamine oxidase (exo-N4-amino)
polyamine oxidase (exo-N4-amino)
polyamine oxidase (exo-N4-amino)
polyamine oxidase (exo-N4-amino)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 10:133379234-133391694
Strand Forward strand
Band q26.3
Transcripts
ENST00000278060 ENSP00000278060
ENST00000357296 ENSP00000349847
ENST00000356306 ENSP00000348654
ENST00000368539 ENSP00000357527
ENST00000368535
ENST00000483211 ENSP00000434550
ENST00000476834 ENSP00000432737
ENST00000480071 ENSP00000435514
ENST00000529585 ENSP00000432517
ENST00000528127
ENST00000530555
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0016491 oxidoreductase activity
GO:0046592 polyamine oxidase activity
GO:0052899 N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity
GO:0052901 spermine:oxygen oxidoreductase (spermidine-forming) activity
GO:0052902 spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity
GO:0052903 N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity
GO:0052904 N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity
Biological Process
GO:0006595 polyamine metabolic process
GO:0006596 polyamine biosynthetic process
GO:0006598 polyamine catabolic process
GO:0006805 xenobiotic metabolic process
GO:0009446 putrescine biosynthetic process
GO:0009447 putrescine catabolic process
GO:0034641 cellular nitrogen compound metabolic process
GO:0044281 small molecule metabolic process
GO:0046203 spermidine catabolic process
GO:0046208 spermine catabolic process
GO:0055114 oxidation-reduction process
GO:1901307 positive regulation of spermidine biosynthetic process
Cellular Component
GO:0005782 peroxisomal matrix
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Metabolism of polyamines pathway
PAOs oxidise polyamines to amines pathway
Amine Oxidase reactions pathway
Metabolism of amino acids and derivatives pathway
Interconversion of polyamines pathway
Metabolism pathway
Biological oxidations pathway
Phase 1 - Functionalization of compounds pathway
KEGG
Peroxisome pathway
INOH
PID BIOCARTA
PID NCI
Alpha9 beta1 integrin signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.532469
RefSeq NM_152911 NM_207127 NM_207128
HUGO
OMIM
CCDS CCDS7682 CCDS7683 CCDS7684
HPRD 10136
IMGT
EMBL
GenPept
RNA Seq Atlas