Version 5.4
Homo sapiens Gene: THRAP3
Summary
InnateDB Gene IDBG-96334.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol THRAP3
Gene Name thyroid hormone receptor associated protein 3
Synonyms TRAP150
Species Homo sapiens
Ensembl Gene ENSG00000054118
Encoded Proteins
IDBP-96336
thyroid hormone receptor associated protein 3
IDBP-600641
thyroid hormone receptor associated protein 3
IDBP-583760
thyroid hormone receptor associated protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:36224416-36305357
Strand Forward strand
Band p34.3
Transcripts
ENST00000354618 ENSP00000346634
ENST00000478853 ENSP00000433066
ENST00000469141 ENSP00000433825
ENST00000466743
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 108 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 108 [view]
Protein-Protein 104 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001104 RNA polymerase II transcription cofactor activity
GO:0003712 transcription cofactor activity
GO:0003713 transcription coactivator activity
GO:0004872 receptor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity
GO:0042809 vitamin D receptor binding
GO:0044822 poly(A) RNA binding
GO:0046966 thyroid hormone receptor binding
GO:0051219 phosphoprotein binding
Biological Process
GO:0000381 regulation of alternative mRNA splicing, via spliceosome
GO:0000956 nuclear-transcribed mRNA catabolic process
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0030518 intracellular steroid hormone receptor signaling pathway
GO:0030521 androgen receptor signaling pathway
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048026 positive regulation of mRNA splicing, via spliceosome
GO:0048255 mRNA stabilization
Cellular Component
GO:0005634 nucleus
GO:0016592 mediator complex
GO:0035145 exon-exon junction complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000043962
View Gene Order
ENSBTAG00000024095
Not yet available
Cross-References
SwissProt Q9Y2W1
TrEMBL E9PML1
UniProt Splice Variant
Entrez Gene 9967
UniGene Hs.160211 Hs.714892
RefSeq NM_005119
HUGO HGNC:22964
OMIM 603809
CCDS CCDS405
HPRD 07543
IMGT
EMBL AC114484 AF117756 AL360074 AL591845 BC037554 BC112330 BC112350 CH471059
GenPept AAD22034 AAH37554 AAI12331 AAI12351 CAH71859 EAX07379 EAX07380
RNA Seq Atlas 9967

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca