Homo sapiens Gene: GNG12
Summary
InnateDB Gene IDBG-99585.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GNG12
Gene Name guanine nucleotide binding protein (G protein), gamma 12
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000172380
Encoded Proteins
guanine nucleotide binding protein (G protein), gamma 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:67701466-67833467
Strand Reverse strand
Band p31.3
Transcripts
ENST00000370982 ENSP00000360021
ENST00000494936
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 22 [view]
Protein-Protein 22 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0030165 PDZ domain binding
GO:0042301 phosphate ion binding
Biological Process
GO:0006112 energy reserve metabolic process
GO:0007165 signal transduction
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007268 synaptic transmission
GO:0021987 cerebral cortex development
GO:0032496 response to lipopolysaccharide
GO:0044281 small molecule metabolic process
GO:0071377 cellular response to glucagon stimulus
Cellular Component
GO:0005834 heterotrimeric G-protein complex
GO:0005884 actin filament
GO:0005886 plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
G alpha (s) signalling events pathway
Integration of energy metabolism pathway
ADP signalling through P2Y purinoceptor 12 pathway
Presynaptic function of Kainate receptors pathway
Transmembrane transport of small molecules pathway
G alpha (12/13) signalling events pathway
Thrombin signalling through proteinase activated receptors (PARs) pathway
Vasopressin regulates renal water homeostasis via Aquaporins pathway
Ca2+ pathway pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
G alpha (q) signalling events pathway
beta-catenin independent WNT signaling pathway
Adrenaline,noradrenaline inhibits insulin secretion pathway
Signaling by Wnt pathway
Neuronal System pathway
Signaling by GPCR pathway
Prostacyclin signalling through prostacyclin receptor pathway
GABA receptor activation pathway
Glucagon signaling in metabolic regulation pathway
G protein gated Potassium channels pathway
Platelet activation, signaling and aggregation pathway
G-protein beta:gamma signalling pathway
Opioid Signalling pathway
Activation of GABAB receptors pathway
Signal Transduction pathway
GPCR downstream signaling pathway
G alpha (i) signalling events pathway
Glucagon-type ligand receptors pathway
G-protein activation pathway
Inwardly rectifying K+ channels pathway
Activation of Kainate Receptors upon glutamate binding pathway
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway
Platelet homeostasis pathway
G alpha (z) signalling events pathway
Potassium Channels pathway
GABA B receptor activation pathway
Thromboxane signalling through TP receptor pathway
Transmission across Chemical Synapses pathway
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits pathway
ADP signalling through P2Y purinoceptor 1 pathway
G beta:gamma signalling through PLC beta pathway
GPCR ligand binding pathway
Regulation of insulin secretion pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Metabolism pathway
G beta:gamma signalling through PI3Kgamma pathway
Signal amplification pathway
Activation of G protein gated Potassium channels pathway
Class B/2 (Secretin family receptors) pathway
Aquaporin-mediated transport pathway
Hemostasis pathway
KEGG
MAPK signaling pathway pathway
Chemokine signaling pathway pathway
Regulation of actin cytoskeleton pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q9UBI6
TrEMBL
UniProt Splice Variant
Entrez Gene 55970
UniGene Hs.431101
RefSeq NM_018841
HUGO HGNC:19663
OMIM 615405
CCDS CCDS30749
HPRD 13592
IMGT
EMBL AF119663 AF123766 AF188181 AF365871 AF493879 AK293101 AL832431 BC005940 CH471059
GenPept AAF04571 AAF17220 AAH05940 AAK53385 AAM12593 AAP97245 BAF85790 CAH10645 EAX06484 EAX06485 EAX06486
RNA Seq Atlas 55970