Version 5.4
Mus musculus Gene: Suv420h1
Summary
InnateDB Gene IDBG-128370.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Suv420h1
Gene Name suppressor of variegation 4-20 homolog 1 (Drosophila)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000045098
Encoded Proteins
IDBP-128372
suppressor of variegation 4-20 homolog 1 (Drosophila)
IDBP-128374
suppressor of variegation 4-20 homolog 1 (Drosophila)
IDBP-252740
suppressor of variegation 4-20 homolog 1 (Drosophila)
IDBP-252742
suppressor of variegation 4-20 homolog 1 (Drosophila)
IDBP-252744
suppressor of variegation 4-20 homolog 1 (Drosophila)
IDBP-252746
suppressor of variegation 4-20 homolog 1 (Drosophila)
IDBP-252748
suppressor of variegation 4-20 homolog 1 (Drosophila)
IDBP-252750
suppressor of variegation 4-20 homolog 1 (Drosophila)
IDBP-541327
suppressor of variegation 4-20 homolog 1 (Drosophila)
IDBP-704891
IDBP-705199
IDBP-704234
IDBP-705210
IDBP-705027
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000110066:
This gene encodes a protein that contains a SET domain. SET domains appear to be protein-protein interaction domains that mediate interactions with a family of proteins that display similarity with dual-specificity phosphatases (dsPTPases). The function of this gene has not been determined. Two alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:3767421-3818303
Strand Forward strand
Band A
Transcripts
ENSMUST00000052699 ENSMUSP00000060162
ENSMUST00000005518 ENSMUSP00000005518
ENSMUST00000113977 ENSMUSP00000109610
ENSMUST00000113974 ENSMUSP00000109607
ENSMUST00000113973 ENSMUSP00000109606
ENSMUST00000113972 ENSMUSP00000109605
ENSMUST00000113970 ENSMUSP00000109603
ENSMUST00000113968 ENSMUSP00000109601
ENSMUST00000155618
ENSMUST00000152935 ENSMUSP00000115984
ENSMUST00000135586
ENSMUST00000177355 ENSMUSP00000135590
ENSMUST00000176407 ENSMUSP00000134897
ENSMUST00000176512 ENSMUSP00000135004
ENSMUST00000176125
ENSMUST00000176926 ENSMUSP00000135756
ENSMUST00000176262 ENSMUSP00000135563
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0018024 histone-lysine N-methyltransferase activity
GO:0042799 histone methyltransferase activity (H4-K20 specific)
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0016571 histone methylation
GO:0034770 histone H4-K20 methylation
GO:0034773 histone H4-K20 trimethylation
Cellular Component
GO:0000780 condensed nuclear chromosome, centromeric region
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000110066
View Gene Order
ENSBTAG00000001185
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00310
Lysine degradation pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00310
Lysine degradation pathway
INOH
PID NCI
reg_gr_pathway
Glucocorticoid receptor regulatory network
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.278578 Mm.392650 Mm.472360
RefSeq NM_001167884 NM_001167885 NM_001167886 NM_001167887 NM_001167888 NM_001167889 NM_144871 XM_006531728
OMIM
CCDS CCDS29399 CCDS50343 CCDS50344 CCDS50345
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca