Version 5.4
Mus musculus Gene: Osbpl1a
Summary
InnateDB Gene IDBG-129085.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Osbpl1a
Gene Name oxysterol binding protein-like 1A
Synonyms G430090F17Rik; Gm753; ORP-1; Osbpl1b
Species Mus musculus
Ensembl Gene ENSMUSG00000044252
Encoded Proteins
IDBP-129091
oxysterol binding protein-like 1A
IDBP-401761
oxysterol binding protein-like 1A
IDBP-401760
oxysterol binding protein-like 1A
IDBP-401759
oxysterol binding protein-like 1A
IDBP-401758
oxysterol binding protein-like 1A
IDBP-401757
oxysterol binding protein-like 1A
IDBP-401756
oxysterol binding protein-like 1A
IDBP-401755
oxysterol binding protein-like 1A
IDBP-401754
oxysterol binding protein-like 1A
IDBP-541467
oxysterol binding protein-like 1A
IDBP-534845
oxysterol binding protein-like 1A
IDBP-539398
oxysterol binding protein-like 1A
IDBP-541458
oxysterol binding protein-like 1A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000141447:
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:12755314-12941841
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000074352 ENSMUSP00000073957
ENSMUST00000119512 ENSMUSP00000113914
ENSMUST00000121808 ENSMUSP00000113841
ENSMUST00000117361 ENSMUSP00000112681
ENSMUST00000121888 ENSMUSP00000112895
ENSMUST00000118313 ENSMUSP00000113735
ENSMUST00000119043 ENSMUSP00000113357
ENSMUST00000121774 ENSMUSP00000113268
ENSMUST00000122175 ENSMUSP00000113491
ENSMUST00000145777
ENSMUST00000143077 ENSMUSP00000122967
ENSMUST00000154614
ENSMUST00000155650 ENSMUSP00000120439
ENSMUST00000124570 ENSMUSP00000122291
ENSMUST00000132594
ENSMUST00000147197 ENSMUSP00000114913
ENSMUST00000141651
ENSMUST00000142467
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015485 cholesterol binding
Biological Process
GO:0006869 lipid transport
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005770 late endosome
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000141447
View Gene Order
ENSBTAG00000023259
Not yet available
Pathways
NETPATH
REACTOME
REACT_230745
Immune System pathway
REACT_196550
MHC class II antigen presentation pathway
REACT_229531
Adaptive Immune System pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_121399
MHC class II antigen presentation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q91XL9
TrEMBL D3Z7I9 Q3V156
UniProt Splice Variant
Entrez Gene 64291
UniGene Mm.259470 Mm.443224 Mm.487415 Mm.490206
RefSeq NM_207530 XM_006526141 XM_006526142 NM_001252489 NM_001252490 NM_001252491 NM_001252492 NM_001252493 XM_006526145 XM_006526146 XM_006526147
OMIM
CCDS CCDS29067 CCDS57114 CCDS57115
HPRD
IMGT
MGI ID MGI:1927551
MGI Symbol Osbpl1a
EMBL AB017026 AC102055 AC131672 AF394063 AK132676 AK168366 AY536214 BC076637
GenPept AAH76637 AAK71661 AAT06024 BAA33012 BAE21296 BAE40301
RNA Seq Atlas 64291

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca