Version 5.4
| Mus musculus Gene: Dcp2 | |||||||||||||
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| Summary | |||||||||||||
| InnateDB Gene | IDBG-144524.6 | ||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
| Gene Symbol | Dcp2 | ||||||||||||
| Gene Name | DCP2 decapping enzyme homolog (S. cerevisiae) | ||||||||||||
| Synonyms | 2410015D23Rik; 5730537H01Rik; AL118268 | ||||||||||||
| Species | Mus musculus | ||||||||||||
| Ensembl Gene | ENSMUSG00000024472 | ||||||||||||
| Encoded Proteins |
DCP2 decapping enzyme homolog (S. cerevisiae)
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
| Entrez Gene | |||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000172795:
The protein encoded by this gene is a key component of an mRNA-decapping complex required for degradation of mRNAs, both in normal mRNA turnover, and in nonsense-mediated mRNA decay (NMD). It removes the 7-methyl guanine cap structure from mRNA, prior to its degradation from the 5' end. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011] |
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| Gene Information | |||||||||||||
| Type | Protein coding | ||||||||||||
| Genomic Location | Chromosome 18:44380500-44424969 | ||||||||||||
| Strand | Forward strand | ||||||||||||
| Band | B3 | ||||||||||||
| Transcripts |
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| Interactions | |||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||
| NETPATH | |||||||||||||
| REACTOME |
Regulation of mRNA stability by proteins that bind AU-rich elements pathway
KSRP destabilizes mRNA pathway
mRNA decay by 5' to 3' exoribonuclease pathway
Gene Expression pathway
Deadenylation-dependent mRNA decay pathway
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| KEGG |
RNA degradation pathway
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| INOH | |||||||||||||
| PID NCI | |||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||
| NETPATH | |||||||||||||
| REACTOME |
Butyrate Response Factor 1 (BRF1) destabilizes mRNA pathway
Tristetraprolin (TTP) destabilizes mRNA pathway
KSRP destabilizes mRNA pathway
mRNA decay by 5' to 3' exoribonuclease pathway
ATF4 activates genes pathway
PERK regulates gene expression pathway
Unfolded Protein Response (UPR) pathway
Deadenylation-dependent mRNA decay pathway
Metabolism of proteins pathway
Regulation of mRNA stability by proteins that bind AU-rich elements pathway
Gene Expression pathway
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| KEGG |
RNA degradation pathway
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| INOH | |||||||||||||
| PID NCI | |||||||||||||
| Cross-References | |||||||||||||
| SwissProt | Q9CYC6 | ||||||||||||
| TrEMBL | |||||||||||||
| UniProt Splice Variant | |||||||||||||
| Entrez Gene | 70640 | ||||||||||||
| UniGene | Mm.368453 Mm.470250 Mm.87629 | ||||||||||||
| RefSeq | NM_027490 | ||||||||||||
| OMIM | |||||||||||||
| CCDS | CCDS50275 | ||||||||||||
| HPRD | |||||||||||||
| IMGT | |||||||||||||
| MGI ID | MGI:1917890 | ||||||||||||
| MGI Symbol | Dcp2 | ||||||||||||
| EMBL | AK017809 AK166560 | ||||||||||||
| GenPept | BAB30946 BAE38853 | ||||||||||||
| RNA Seq Atlas | 70640 | ||||||||||||