Version 5.4
Mus musculus Gene: Rreb1
Summary
InnateDB Gene IDBG-145333.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rreb1
Gene Name ras responsive element binding protein 1
Synonyms 1110037N09Rik; AA414966; B930013M22Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000039087
Encoded Proteins
IDBP-145335
ras responsive element binding protein 1
IDBP-260692
ras responsive element binding protein 1
IDBP-260694
ras responsive element binding protein 1
IDBP-542344
ras responsive element binding protein 1
IDBP-541157
ras responsive element binding protein 1
IDBP-534801
ras responsive element binding protein 1
IDBP-538781
ras responsive element binding protein 1
IDBP-536694
ras responsive element binding protein 1
IDBP-532915
ras responsive element binding protein 1
IDBP-537333
ras responsive element binding protein 1
IDBP-540414
ras responsive element binding protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124782:
The protein encoded by this gene is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:37778400-37952002
Strand Forward strand
Band A3.3
Transcripts
ENSMUST00000037232 ENSMUSP00000049265
ENSMUST00000110238 ENSMUSP00000105867
ENSMUST00000110237 ENSMUSP00000105866
ENSMUST00000122842 ENSMUSP00000117048
ENSMUST00000138043 ENSMUSP00000124745
ENSMUST00000128570 ENSMUSP00000115599
ENSMUST00000149745 ENSMUSP00000121211
ENSMUST00000124373 ENSMUSP00000118420
ENSMUST00000138110 ENSMUSP00000116557
ENSMUST00000124268 ENSMUSP00000118262
ENSMUST00000162849 ENSMUSP00000124802
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0016607 nuclear speck
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000124782
View Gene Order
ENSBTAG00000005980
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.132634 Mm.401338 Mm.482689
RefSeq NM_001039188 NM_001177868 NM_001177869 NM_026830 XM_006516749 XM_006516750 XM_006516751 XM_006516752 XM_006516753 XM_006516754 XM_006516755 XM_006516756 XM_006516757 XM_006516759 XM_006516760
OMIM
CCDS CCDS36634 CCDS49238
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca