Version 5.4
| Homo sapiens Gene: ABCA2 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-92973.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | ABCA2 | ||||||||||||||||||
| Gene Name | ATP-binding cassette, sub-family A (ABC1), member 2 | ||||||||||||||||||
| Synonyms | ABC2 | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000107331 | ||||||||||||||||||
| Encoded Proteins |
ATP-binding cassette, sub-family A (ABC1), member 2
ATP-binding cassette, sub-family A (ABC1), member 2
ATP-binding cassette, sub-family A (ABC1), member 2
ATP-binding cassette, sub-family A (ABC1), member 2
ATP-binding cassette, sub-family A (ABC1), member 2
ATP-binding cassette, sub-family A (ABC1), member 2
ATP-binding cassette, sub-family A (ABC1), member 2
ATP-binding cassette, sub-family A (ABC1), member 2
ATP-binding cassette, sub-family A (ABC1), member 2
ATP-binding cassette, sub-family A (ABC1), member 2
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| Protein Structure | |||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 9:137007227-137028922 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | q34.3 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
ABCA transporters in lipid homeostasis pathway
ABC-family proteins mediated transport pathway
Transmembrane transport of small molecules pathway
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| KEGG |
ABC transporters pathway
Lysosome pathway
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| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | |||||||||||||||||||
| TrEMBL | |||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 20 | ||||||||||||||||||
| UniGene | Hs.421202 Hs.679065 | ||||||||||||||||||
| RefSeq | NM_001606 NM_212533 XM_006716996 | ||||||||||||||||||
| HUGO | HGNC:32 | ||||||||||||||||||
| OMIM | 600047 | ||||||||||||||||||
| CCDS | CCDS43909 | ||||||||||||||||||
| HPRD | 08967 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | |||||||||||||||||||
| GenPept | |||||||||||||||||||
| RNA Seq Atlas | 20 | ||||||||||||||||||