Mus musculus Gene: Med12l
Summary
InnateDB Gene IDBG-146676.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Med12l
Gene Name mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)-like
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000056476
Encoded Proteins
mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)-like
mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)-like
mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)-like
mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000144893:
The protein encoded by this gene is part of the Mediator complex, which is involved in transcriptional coactivation of nearly all RNA polymerase II-dependent genes. The Mediator complex links gene-specific transcriptional activators with the basal transcription machinery. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:59006978-59318410
Strand Forward strand
Band D
Transcripts
ENSMUST00000040846 ENSMUSP00000041859
ENSMUST00000029393 ENSMUSP00000029393
ENSMUST00000040325 ENSMUSP00000042269
ENSMUST00000164225 ENSMUSP00000127038
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001104 RNA polymerase II transcription cofactor activity
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
Biological Process
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0008150 biological_process
Cellular Component
GO:0016592 mediator complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL H7BX07
UniProt Splice Variant
Entrez Gene 329650
UniGene Mm.240059
RefSeq NM_177855 XM_006501585 XM_006501586 XM_006501587 XM_006501588 XM_006501590
OMIM
CCDS
HPRD
IMGT
MGI ID MGI:2139916
MGI Symbol Med12l
EMBL AC115919 AC122038
GenPept
RNA Seq Atlas 329650